The familial connection is one of the Strongest Indicators of Risk according to Experts.

ECAN spoke with the Leading Researcher in Familial Links in Barrett’s Esophagus and Esophageal Cancer about the Latest in Research and How Families can become Involved.  Dr. Amitabh Chak of Case Western Reserve University is the leading authority on research into the familial links in Barrett’s Esophagus and Esophageal Adenocarcinoma. He provides information about what percentage of cases are thought to have familial links, the latest guidelines from professional organizations about who should be screened in light of familial connections with Barrett’s and Esophageal Adenocarcinoma, the state of current research, and how patients and families can become involved in the research.

May 2016, Predicting Barrett’s esophagus in Families: An Esophagus Translational Research Network (BETRNet) Model Fitting Clinical Data to a Familial Paradigm, Cancer Epidemiol Biomarkers Prev
https://cebp.aacrjournals.org/content/25/5/727.long
October 2016, Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia, JAMA Oncology
https://jamanetwork.com/journals/jamaoncology/fullarticle/2537186?utm_campaign=articlePDF%26utm_medium%3darticlePDFlink%26utm_source%3darticlePDF%26utm_content%3djamaoncol.2016.2054